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. 2014 May 5;9(5):e96610. doi: 10.1371/journal.pone.0096610

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© 2014 Luo et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

(A) Expression of c-Jun, cystatin A, involucrin or SPRR3 was examined in human ESCC using TMA on 110 pairs of ESCCs and their corresponding nontumor tissues by immunohistochemistry. (B) Statistical analysis was performed using SPSS17.0 software. c-Jun and differentiation-associated genes were significantly down-regulated in ESCC.