Table 3. Common altered mRNAs (including class III) extracted from 11 human cancers using digital differential display (DDD), together with the available online microarray.

Gene symbol	location	PCSR	Cancer cell type																						Expression class
			Breast		Endometrial		Ovarian		Prostate		Testicular		Colorectal		Liver		Gastric		Pancreatic		Glioblastoma		Lung
			M	D	M	D	M	D	M	D	M	D	M	D	M	D	M	D	M	D	M	D	M	D
ZEB2	chr2q22.3	✓	↓		↓		↓		↓		↓		↓				↑				↓		↓		Class III
ZEB1	chr10p11.22	-			↓		↓		↑		↓		↓		↑		↑				↑		↓		Class III
KRT8	chr12q13.13	-	↑		↑	↑			↑	↑	↑		↓	↑	↓	↑		↑		↑		↑	↑	↑	Class III
ANXA2	chr15q22.2	✓			↑	↑	↓			↑	↓				↑	↑	↑		↑	↑		↑			Class III
IGF2BP3	chr7p11	✓			↑		↑		↑		↑		↑		↑		↑		↑		↓		↑		Class III
DDX5	chr17q23.3	-			↓	↓	↓			↓	↑	↓	↓									↓	↓	↓	Class III
CD24	chryq11.22	✓	↑		↑	↑	↑		↑	↓	↑	↑		↓	↑		↓					↑	↑		Class III
TOP2A	chr17q21.2	✓	↓		↑		↑				↑		↑		↑		↑		↑		↑		↑		Class III
DCN	chr12q21.33	✓			↓		↓		↓		↓		↓		↓			↓	↑			↓	↓	↓	Class III
CENPF	chr1q41	-	↑		↑		↑				↑		↑		↑		↑				↑		↑		Class III
LIFR	chr5p13.1	✓	↓		↓		↓				↑		↓		↓		↓						↓		Class III
ABCA8	chr17q24.2	✓	↓		↓		↓		↑		↓		↓		↓		↓						↓		Class III
COL11A1	chr1p21.1	✓	↑		↑		↓				↑		↑		↑		↑		↑				↑		Class III
RSAD2	chr2p25.2	✓	↑		↑		↑				↑		↓				↓		↑		↑				Class III
Cd36	chr7q21.11	✓	↓		↓		↓		↑				↓				↓				↑				Class III
PCDH7	chr4p15.1	✓	↑		↓		↑		↑		↑		↓						↑				↑		Class III
PKIB	chr6q22.31	✓	↑		↓				↓		↑		↓		↑		↓		↓		↓		↑		Class III
EDNRB	chr13q22.3	✓	↑		↑		↑		↑		↑		↑		↑						↓		↑		Class III
SULF1	chr8q13.1	✓	↑		↑		↓				↓		↑		↑		↑		↑		↑		↑		Class III
DIO2	chr14q31.1	✓	↑				↑		↑		↓		↑				↑		↑				↑		Class III
TMC5	chr16p12.3	✓	↑		↑		↑		↑		↓				↑				↑				↓		Class III
HS6ST2	chrXq26.2	✓			↓		↓		↓		↑		↑		↑		↑		↓				↑		Class III
PTGS2	chr1q31.1	✓	↓				↓				↓				↓				↑				↓		Class III
GPM6A	chr4q34.2	✓	↓		↓		↓		↓		↑		↓		↓						↑		↓		Class III
C7	chr5p13.1	✓	↓		↓	↓	↓		↓			↓	↓		↓						↑		↓		Class III
MT1M	chr16q12.2	✓	↓						↓		↑		↓		↓		↓				↑		↓		Class III

Abbreviations: PCSR, Potential Cancer-Susceptibility Region; M, Microarray; D, Digital Differential Display.

Symbols: ↑, over-expression; ↓, down-expression; ✓, risk region.