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. 2014 May 5;9(5):e96581. doi: 10.1371/journal.pone.0096581

Table 1. Characteristics of included studies.

Author/Year Country Population Comparisons Follow-up Quality
1.Arthur 2002 13 Canada CABG patients (N = 242). Participating in a Cardiac Rehabilitation program: Yes Intervention: In addition to exercise, patients were telephoned every 2 weeks by the exercise specialist. Comparison: Hospital based exercise training 6 months High quality
2.Bambauer 2005 14 USA ACS patients (N = 100). Participating in a Cardiac Rehabilitation program: Not described Intervention: Six 30 minute telephone counseling sessions. Comparison: Patients received a booklet on coping with chronic illness and were instructed to contact their primary care physician if they experienced any warning signs of more significant depression. 6 months Acceptable
3.Bazargani 2011 15 Iran CABG patients (N = 300). Participating in a Cardiac Rehabilitation program: Yes Intervention: 6 sessions (150 min/week) of psycho-education. Comparison: Not described 3 months Unacceptable
4.Beckie 1989 16 Canada CABG patients (N = 74). Participating in a Cardiac Rehabilitation program: Not described Intervention: 4 to 6 supportive-educative telephone calls with a cardiac rehabilitation nurse specialist. Comparison: Received routine in-hospital teaching available to all patients undergoing cardiac surgery. 1.5 months Acceptable
5.Gallagher 2003 17 Australia Women with CAD (N = 196). Participating in a Cardiac Rehabilitation program: 32% did Intervention: 4 telephone calls to assist coping with recovery. Comparison: All inpatients received a Phase I education program, and all women were referred to local cardiac rehabilitation programs. 3 months Acceptable
6.Hanssen 2007 18 Norway AMI patients (N = 288). Participating in a Cardiac Rehabilitation program: Not described Intervention: Nurse-initiated telephone calls after discharge. Comparison: All patients in the control group were managed in accordance with the current clinical practice, which encompassed one visit to a physician at the outpatient clinic 6–8 weeks after discharge, and subsequent visits to the patient's general practitioner. 6 months Acceptable
7.Hanssen 2009 19 Norway AMI patients (N = 288). Participating in a Cardiac Rehabilitation program: A very small proportion were referred Intervention: Nurse-initiated telephone calls after discharge. Comparison: All patients in the control group were managed in accordance with the current clinical practice, which encompassed one visit to a physician at the outpatient clinic 6–8 weeks after discharge, and subsequent visits to the patient's general practitioner. 18 months Acceptable
8.Hartford 2002 20 Canada CABG patients (N = 166) who have a caregiver. Participating in a Cardiac Rehabilitation program: Not described Intervention: 6 telephone calls to patients and partners. Comparison: The control group received usual care, which did not include systematic follow-up 2 months High quality
9.Holmes-Rovner 2008 21 USA ACS patients (N = 525). Participating in a Cardiac Rehabilitation program: Not described Intervention: Six-session telephone counseling calls by a health educator. Comparison: Patients received a written discharge contract listing recommended outpatient medications, cardiac rehabilitation recommendations, and health behavior changes (smoking cessation, diet modification, and exercise), as well as numerical values for ejection fraction and cholesterol. 8 months Acceptable
10.Ma 2010 22 USA CAD patients (N = 689). Participating in a Cardiac Rehabilitation program: Not described Intervention: Pharmacist-delivered telephone counseling calls. Comparison: consisted of normal clinical care as determined by the patient's provider. 12 months Acceptable
11.Mclaughlin 2005 23 USA ACS patients (N = 100) with symptoms of depressive illness or anxiety. Participating in a Cardiac Rehabilitation program: Not described Intervention: 3–6 telephone counseling sessions of 30 minutes by clinicians. Comparison: Patients received a booklet on coping with cardiac illness typical of those given at hospital discharge and were instructed to contact their primary care physician if they experienced any warning signs of depression. 6 months Acceptable
12.Mittag 2006 24 Germany CAD patients (N = 343). Participating in a Cardiac Rehabilitation program: All received 3 weeks of inpatient Cardiac Rehabilitation Intervention: Monthly nurse-initiated telephone contacts. Comparison: The control group received six flyers on general health topics (relaxation, sports and physical exercise, sleep disorders, low back pain, nutrition) by mail every second month as an attention placebo. Patients in the intervention group were given the same written information 12 months Acceptable
13.Neubeck 2009 25 Australia ACS patients (N = 208). Participating in a Cardiac Rehabilitation program: Not accessing CR Intervention: A clinic visit plus 3 months of phone support. Comparison: ongoing conventional health care. Managing cardiovascular health in consultation with their GP and cardiologist. 48 months Acceptable
14.Neubeck 2011 26 Australia ACS patients (N = 208). Participating in a Cardiac Rehabilitation program: Not accessing CR Intervention: 1-hour consultation and telephone calls over 3 months. Comparison: ongoing conventional health care. Managing cardiovascular health in consultation with their GP and cardiologist. 48 months High quality
15.Redfern 2008 27 Australia ACS patients (N = 208). Participating in a Cardiac Rehabilitation program: Not accessing CR Intervention: 1-hour consultation and approximately four 10-minute follow-up calls. Comparison: Participants continued to manage their cardiovascular health as directed by their family physician often in consultation with their cardiologist. 3 months High quality
16.Redfern 2009 28 Australia ACS patients (N = 208). Participating in a Cardiac Rehabilitation program: Not accessing CR Intervention: Clinic visit plus telephone support and tailored preferential risk modification. Comparison: continuing conventional care but no centrally coordinated secondary prevention 12 months High quality
17.Redfern 2010 29 Australia ACS patients (N = 208). Participating in a Cardiac Rehabilitation program: Not accessing CR Intervention: One-hour initial consultation and four 10 minute follow-up phone calls over three months. Comparison: participated in ongoing conventional care, aimed at managing their cardiovascular health as directed by their General Practitioner, ideally in consultation with their Cardiologist. 12 months High quality
18.Reid 2007 30 Canada CAD patients (N = 100) who were also current smokers. Participating in a Cardiac Rehabilitation program: Not described Intervention: Automatic telephone contact plus counseling by up to three 20-min telephone sessions. Comparison: All participants received advice to quit smoking; access to Nicotine Replacement Therapy during hospitalization (if necessary); brief bedside counseling with a nurse-specialist; a self-help guide; and the provision of information about the hospital's outpatient smoking cessation program and other community programs. 12 months High quality
19.Smith 2004 31 Canada CABG patients (N = 222). Participating in a Cardiac Rehabilitation program: All participated in CR (home vs. hospital-based) Intervention: Exercise program and telephone follow-up every 2 weeks by an exercise specialist. Comparison: Patients assigned to the Hospital based exercise group were expected to attend supervised exercise sessions 3 times per week for 6 months. 12 months High quality
20.Smith 2007 32 Canada CABG patients (N = 196). Participating in a Cardiac Rehabilitation program: All participated in CR (home vs. hospital-based) Intervention: Exercise program and telephone follow-up every 2 weeks by an exercise specialist. Comparison: Patients assigned to the Hospital based exercise group were expected to attend supervised exercise sessions 3 times per week for 6 months. 72 months High quality
21.Smith 2011 33 Canada CABG patients (N = 196). Participating in a Cardiac Rehabilitation program: All participated in CR (home vs. hospital-based) Intervention: Exercise program and telephone follow-up every 2 weeks by an exercise specialist. Comparison: Patients assigned to the Hospital based exercise group were expected to attend supervised exercise sessions 3 times per week for 6 months. 72 months High quality
22.Stevens 1985 34 Canada MI patients (N = 59). Participating in a Cardiac Rehabilitation program: Not described Intervention: Received telephone calls by 2 nurses and the investigator. Comparison: nurses educated MI patients prior to discharge and all got a booklet to take home. Upon discharge patients were returned to the care of the GP and received usual follow-up. 1.5–2 months High quality
23.Tranmer 2004 35 Canada CAD patients (N = 200). Participating in a Cardiac Rehabilitation program: Not described Intervention: Follow-up via nurse-initiated telephone calls. Comparison: Usual care included preoperative and discharge preparation by the nurse, provision of an education booklet and home care follow-up, as necessary. 1.25 months High quality
24.Vale 2003 36 Australia CAD patients (N = 792). Participating in a Cardiac Rehabilitation program: 53% of patients in the intervention group and 57% of the patients in the control group attended a cardiac rehabilitation program. Intervention: Patients received coaching sessions by telephone. Comparison: Patients received a hospital discharge summary, a one page chart of risk factor for CHD secondary prevention to them and their medical caregivers as well as contacted once after discharge at 24 weeks for follow-up assessment 6 months High quality
25.Vale 2002 37 Australia CABG or PCI patients (N = 245). Participating in a Cardiac Rehabilitation program: 53% of patients in the intervention group and 50% of the patients in the control group attended a cardiac rehabilitation program. Intervention: Dietitian contacted patients 5 times by telephone regarding lipid levels. Comparison: All patients in the study (including patients in the coaching intervention group) were offered information about a cardiac rehabilitation program and were encouraged to attend. Patients in the usual care group were contacted at 24 weeks postrandomization to obtain a fasting serum lipid profile within the next 2 weeks. 6 months High quality
26.Van Elderen 1994 38 USA AMI patients (N = 60). Participating in a Cardiac Rehabilitation program: Not described Intervention: Nurse contacted the patient by telephone. Comparison: Patients received standard medical care only; consisting primarily of medical care. A standard physical rehabilitation program was mplemented in the nursing ward. 12 months Acceptable

Note: Studies underlined and in bold were included in the meta-analysis. The other studies were described qualitatively. CABG = Coronary artery bypass graft. ACS = Acute coronary syndrome. AMI = Acute myocardial infarction. CAD = Coronary artery disease. PCI = Percutaneous coronary intervention.