Table 9. Accuracy of active tuberculosis diagnosis by the serology test based on the ELISA using the PGL-Tb1, ESAT-6/CFP10 or both antigens in ATB patients (pulmonary and extrapulmonary TB) stratified by HIV status.

PGL-Tb1*	HIV-infected	HIV-infected + HIV-unknown	Total
Sensitivity (95% CI)	72.3 (62.4–80.7)	40.5 (36.8–44.3)	44.7 (41.2–48.3)
Specificity (95% CI)	90.9 (88.2–93.1)	90.9 (88.2–93.1)	90.9 (88.2–93.1)
PPV (95% CI)	58.9 (49.7-67.6)	84.3 (79.9–88.1)	87.2 (83.5–90.3)
NPV (95% CI)	94.8 (92.5–96.5)	55.8 (52.5–59.1)	54.2 (50.9–57.4)
LR+	7.93	4.44	4.90
LR-	3.31	1.53	1.65

Footnotes: TB: tuberculosis; HIV: human immunodeficiency virus; n/N = number of positive tests/number of tested sera in each group; * Cut-off value for PGL-Tb1: OD = 0.130; ** Cut-off value for ESAT-6/CFP10: OD = 0.100; CI: confidence interval; PPV: positive predictive value; NPV: negative predictive value; LR+: positive likelihood ratio; LR-: negative likelihood ratio.