Table 13. Comparison of the sensitivity of the TST and the serology test based on ELISA using each antigen and their cumulative results in HIV-infected active TB patients stratified by CD4 cell counts/µL (lower or above 200/µL).
Percentage (95% CI) | |||||
n/N | <200 CD4 cell counts/µL | n/N | >200 CD4 cell counts/µL | P | |
% (95% CI) | % (95% CI) | ||||
ELISA | |||||
PGL-Tb1 | 22/36 | 61.1 (43.5–76.9) | 15/20 | 75.0 (50.9–91.3) | 0.3824 |
ESAT-6/CFP10 | 22/36 | 61.1 (43.5–76.9) | 14/20 | 70.0 (45.7–88.1) | 0.5713 |
Both antigens | 24/36 | 66.7 (49.0–81.4) | 15/20 | 75.0 (50.9–91.3) | 0.5613 |
TST | 9/11 | 81.8 (48.2–97.7) | 3/4 | 75.0 (19.4–99.4) | 1.000 |
Footnotes: TB: tuberculosis; HIV: human immunodeficiency virus; n/N = number of positive tests/number of tested sera in each group; TST: tuberculin skin test (cut-off 5 mm); Cut-off value for PGL-Tb1: OD = 0.130; Cut-off value for ESAT-6/CFP10: OD = 0.100; CI: confidence interval.