Skip to main content
. 2013 Nov 14;5(5):179–187. doi: 10.4161/isl.26980

Table 1. Published PET tracers for visualizing transplanted islets.

Method for labeling Tracer References Radioactivity Islet donor species Comments
Labeling of islets directly [18F]FDG 17 , 33 4–6 h human, rat Available for clinical use already
Short radioactivity
High uncharacteristic washout
[18F]FHBG 18 - 20 1–3 mo human, rat, mouse Longer radioactivity
Use of viral vector
Labeling of islets via intravenous infusion [11C]DTBZ 23 Approximately 30 min rat Specific labeling of islets via VMAT2
Short radioactivity
[64Cu]/[18F]-labeled exendin-4 26 , 36 Over 4 h human Specific labeling of islets via GLP-1 receptor
[18F]- labeled fallypride 30 Over 1.5 h rat Specific labeling of islets via D2/D3 receptor
Available for clinical use already
Binds to other organs (mainly the brain)
[68Ga]-labeled biotin 32 Over 30 min human Specific labeling of islets via avidin-biotin interaction
Prevention of IBMIR