Skip to main content
. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Xenotransplantation. 2013 Nov 5;21(1):72–83. doi: 10.1111/xen.12073

Figure 2. Anti-coagulant agents inhibit human platelet aggregation induced by WT pAEC.

Figure 2

Preincubation of human whole blood and WT pAEC with an anti-thrombin agent (heparin, LMWH at 1 or 5IU/mL, or hirudin at 1 or 5IU/mL) reduced platelet aggregation. Heparin at 1IU/mL (3% aggregation), LMWH at 5IU/ml (3% aggregation), and hirudin at 5IU/mL (4% aggregation) completely prevented aggregation, while LMWH (15%) and hirudin (29%) at 1IU/mL had a partial effect when compared with control (54%). (*p<0.05, **p<0.01).