Table 2.

Fold change of miRNAs as compared to normal thyroid tissue.

Assay	PD origin PTC (RQ)	PD origin PTC (P- Value)	onc PD (RQ)	onc PD (P- Value)	FTC min inv ACO (RQ)	FTC min inv ACO (P- Value)	FTC min inv CG (RQ)	FTC min inv CG (P- Value)	onc FTC min inv ACO (RQ)	onc FTC min inv ACO (P- Value)	onc FTC min inv CG (RQ)	onc FTC min inv CG (P- Value)	FVPTC ACO (RQ)	FVPTC ACO (P- Value)	FVPTC CG (RQ)	FVPTC CG (P- Value)	classic PTC ACO (RQ)	classic PTC ACO (P- Value)	classic PTC CG (RQ)	classic PTC CG (P- Value)
hsa-miR-125a-5p	1.5102	0.4881	2.4358	0.0187	1.2707	0.4421	1.6433	0.2316	4.0741	0.3049	4.7852	0.0075	2.5696	0.2219	1.7166	0.066	1.4341	0.3937	2.1557	0.5639
hsa-miR-130b	0.8801	0.9389	0.1602	0.0187	1.783	0.6458	2.5355	0.2316	1.731	0.7234	0.3676	0.0926	0.4902	0.2219	2.3146	0.3188	0.6463	0.3937	0.7208	0.6894
hsa-miR-139-5p	0.1707	0.0201	0.3858	0.1434	0.677	0.4421	0.388	0.0238	0.536	0.3049	0.7897	0.507	0.6616	0.2219	0.3725	0.066	0.2414	0.0066	0.405	0.0453
hsa-miR-150	0.1761	0.0504	0.2722	0.0947	0.354	0.2963	0.1426	0.103	0.4136	0.3049	0.2988	0.134	0.6563	0.4591	0.2031	0.1116	0.7581	0.5937	1.3036	0.6661
hsa-miR-15a-3p	5.1826	0.0504	4.6616	0.1309	5.1007	0.2963	3.3332	0.1252	8.4616	0.4806	4.7142	0.1786	5.0306	0.1008	3.7938	0.1657	4.9066	0.0628	8.3654	0.5639
hsa-miR-182	4.1321	0.3134	15.7878	0.0102	3.0254	0.4586	5.8046	0.103	10.0218	0.3049	17.0327	0.1449	4.4518	0.2219	1.7252	0.5809	2.4388	0.0383	3.2818	0.6282
hsa-miR-183-3p	7.529	0.099	13.6166	0.0102	3.388	0.4118	10.2013	0.0027	10.4589	0.3049	29.1113	0.0667	2.4758	0.2219	8.1253	0.1401	1.5139	0.5937	3.393	0.5639
hsa-miR-193a-5p	0.1959	0.0504	0.2206	0.0105	0.3138	0.2352	0.2039	0.0053	0.4504	0.3049	0.288	0.0075	0.5907	0.2125	0.4214	0.066	0.2925	0.0066	0.4258	0.0639
hsa-miR-219-5p	0.0301	0.0504	0.006	0.009	0.0132	0.2963	0.0415	0.231	0.1188	0.3049	0.0102	0.1786	0.1312	0.2219	0.0422	0.178	0.0093	---	0.1217	0.4679
hsa-miR-221	0.9105	0.9788	12.2539	0.0081	4.3356	0.4118	5.1579	0.1045	17.4066	0.3049	29.5232	0.0075	13.3133	0.0649	19.4575	0.066	8.8605	0.0692	8.4463	0.0453
hsa-miR-222	1.6391	0.8249	9.7331	0.0081	4.8395	0.2963	4.9973	0.2857	7.3821	0.3049	7.0607	0.0084	27.2159	0.1829	11.7024	0.0853	13.9184	0.001	19.3691	0.4679
hsa-miR-222-5p	1.2917	0.9389	7.2611	0.0491	1.2929	0.6677	1.5184	0.5663	4.754	0.4118	5.5375	0.0192	2.8774	0.1599	11.8716	0.264	1.4406	0.5676	1.4444	0.6379
hsa-miR-23b	0.7987	0.8369	0.1962	0.0466	0.9723	0.9397	1.4223	0.3509	1.0668	0.9409	0.745	0.5174	1.3934	0.4802	2.2949	0.1401	0.7094	0.5228	0.8915	0.804
hsa-miR-451	0.2865	0.0504	0.4047	0.2194	0.3729	0.2963	0.4661	0.1612	0.4923	0.3049	0.2964	0.0447	0.3157	0.1008	0.3498	0.089	0.1935	0.0292	0.2783	0.1313
hsa-miR-455-3p	0.406	0.4881	0.1474	0.0454	0.2969	0.2963	0.141	0.103	1.2864	0.8904	0.0566	0.0447	0.4076	0.2219	0.2612	0.1116	0.3434	0.1663	0.7686	0.6661
hsa-miR-885-5p	1.917	0.7069	42.8892	0.0204	0.2762	0.2963	1.1838	0.739	105.7278	0.575	520.8887	0.3223	0.7637	0.5749	0.8291	0.6616	15.8382	0.4348	4.2795	0.6155
hsa-miR-886-3p	0.1247	0.0504	0.2513	0.1482	0.3488	0.3146	0.4431	0.2978	0.3415	0.3049	0.779	0.6609	0.5886	0.4591	0.1852	0.1401	0.3833	0.3051	0.5471	0.5639

P-values are indicated in relation to normal thyroid tissue. PTC = Papillary Thyroid Carcinoma; FVPTC = Follicular Variant of Papillary Thyroid Carcinoma; FTC min. inv. = Minimally Invasive Thyroid Carcinoma; PD = Poorly differentiated Thyroid Carcinoma; oFTC min. inv. = Oncocytic Minimally Invasive Thyroid Carcinoma; oPD = Oncocytic Poorly differentiated Thyroid Carcinoma. ACO = Adverse Clinical Outcome; CG = Control Group