Table 1.
Donor clinical and demographic data
| Variable | Perfusion Only (n = 4) | MSC (n = 4) | MSC with KGF Antibody (n = 3) | MSC with IgG Antibody Control (n = 3) |
|---|---|---|---|---|
| Mean age, yr | 51 ± 5 | 51 ± 13 | 57 ± 5 | 38 ± 17 |
| Female, % | 25 | 50 | 66 | 0 |
| Donor P/F ratio | 197.9 ± 81.1 | 190.9 ± 88.4 | 271.3 ± 114.3 | 375.7 ± 158.4 |
| Donor Lung Compliance, ml/cmH2O | 40 ± 17 | 44 ± 6 | 37 ± 3 | 37 ± 11 |
| PEEP | 10 ± 2 | 7 ± 2 | 5 ± 0 | 7 ± 2 |
| CXR infiltrates | 3 ± 1 | 3 ± 1 | 2 ± 1 | 3 ± 1 |
| Acute lung injury score | 2.6 ± 0.7 | 2.1 ± 0.8 | 1.5 ± 0.8 | 1.7 ± 0.8 |
| Ischemic time, h | 31 ± 6 | 33 ± 31 | 24 ± 14 | 29 ± 14 |
Data are expressed as means ± SD; n, no. of lungs.
MSC, mesenchymal stem cell; KGF, keratinocyte growth factor; PEEP, positive end-expiratory pressure; CXR, chest X-ray.
Acute lung injury score based on maximum of 4 points for the PaO2-to-FiO2 ratio (P/F), level of positive end-expiratory airway pressure, quasistatic respiratory compliance, and the extent of chest radiographic infiltrates.