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. 2014 Feb 4;306(9):E1013–E1024. doi: 10.1152/ajpendo.00553.2013

Fig. 1.

Fig. 1.

Protein abundance of insulin receptor substrate (IRS-1), phosphatidylinositol 3-kinase (PI3K; p85), PI3K (p110β), and phosphatase and tensin homolog (PTEN) in singleton and twin fetuses in late gestation. Abundance of IRS-1, p110β, and PTEN protein was lower in singletons (A, C, and D), and abundance of IRS-1, p85, p110β, and PTEN protein was higher in twins (E, F, G, and H) in the periconceptional undernutrition (PCUN) and preimplantation undernutrition (PIUN) groups compared with controls. p85 protein abundance was not different in singletons in either treatment group (B). Different letters denote significant differences between treatment groups.