Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Feb 26;306(9):F996–F1007. doi: 10.1152/ajprenal.00657.2013

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

PMC Copyright notice

Fig. 4. — Increasing PKG activity reduced transforming growth factor (TGF)-β/Smad pathway in a UUO mouse model. A–D: kidney TGF-β1 mRNA and protein levels from UUO or sham group of mice were determined by real-time PCR and Western blotting, respectively. E: kidney sections from mice were stained with anti-TGF-β1 antibody. The positive staining is shown as brown. Representative light micrographs are shown. F and G: pSmad2 protein levels in kidney cortex from UUO or sham group of mice were determined by Western blotting. Data are presented as means ± SE (n = 5–6 mice/group). *P < 0.05 vs. WT/sham group or saline group. #P < 0.05 vs. WT/UUO group. &P < 0.05 vs. Tg/sham group.

Fig. 4. — Increasing PKG activity reduced transforming growth factor (TGF)-β/Smad pathway in a UUO mouse model. A–D: kidney TGF-β1 mRNA and protein levels from UUO or sham group of mice were determined by real-time PCR and Western blotting, respectively. E: kidney sections from mice were stained with anti-TGF-β1 antibody. The positive staining is shown as brown. Representative light micrographs are shown. F and G: pSmad2 protein levels in kidney cortex from UUO or sham group of mice were determined by Western blotting. Data are presented as means ± SE (n = 5–6 mice/group). *P < 0.05 vs. WT/sham group or saline group. #P < 0.05 vs. WT/UUO group. &P < 0.05 vs. Tg/sham group.