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. 2014 Mar 5;306(9):F1059–F1068. doi: 10.1152/ajprenal.00015.2014

Table 1.

Physiologic responses to infusions of KCl and NaCl

Uninfused KCl Infused NaCl Infused
Infusion volume, ml/3 h 0 12 ± 0 2.92 ± 0.36
Infused K, mmol 0 1363 ± 54 0
Infused Na+, mmol 0 452 ± 56 452 ± 56
Urinary volume, ml/3 h 0.96 ± 0.17 4.9 ± 0.64 * 1.1 ± 0.3
Hematocrit, %
    Initial 45.3 ± 1.4 45.8 ± 0.5 44.6 ± 0.7
    After 3 h 45.0 ± 1.5 38.6 ± 1.0 41.8 ± 0.7

Values are means ± SE. KCl infusion group was infused with 150 mM KCl at a variable rate to elevate and maintain the plasma K+ concentration to 5.5 mM and 0.9% saline was concurrently infused to maintain an overall volume infusion rate of 4 ml/h over 3 h. NaCl infusion group received the same amount of NaCl that was infused into the KCl rats in a paired fashion. Uninfused group was prepared in the same manner but not infused. Infused K+ and Na+ and volumes were calculated from the infusion rate, recorded every 15 min, and the concentrations infused.

*

P < 0.05 in KCl infused vs. NaCl infused.

P < 0.05 before vs. after infusion.