Table 2.
Top 50 genes upregulated in 3D + HGF but not in 2D + HGF
| Gene Symbol | Affymetrix Probeset ID | Fold Change in 2D + HGF | Fold Change in 3D + HGF | MAPK 3D | |
|---|---|---|---|---|---|
| 1 | MMP1 | CfaAffx.23166.1.S1_s_at | 1.7815 | 74.6253 | Yes |
| 2 | MAP3K5 | Cfa.14238.1.A1_s_at | −1.3043 | 24.5208 | Yes |
| 3 | TXNRD1 | Cfa.8894.1.A1_s_at | −1.20665 | 19.466 | No |
| 4 | WDR37 | Cfa.7195.1.A1_at | 1.69907 | 18.4215 | Yes |
| 5 | LRRC59 | CfaAffx.26063.1.S1_at | 1.70389 | 16.8271 | Yes |
| 6 | GPC3 | Cfa.2467.1.S1_at | −1.27932 | 13.7171 | Yes |
| 7 | DKC1 | Cfa.15181.1.A1_s_at | −1.09159 | 12.1819 | No |
| 8 | FANCM | CfaAffx.21714.1.S1_s_at | 1.91544 | 11.6979 | Yes |
| 9 | DKC1 | Cfa.19618.1.S1_s_at | 1.12708 | 10.488 | No |
| 10 | CCDC99 | Cfa.18573.1.S1_at | 1.3448 | 10.4055 | Yes |
| 11 | FARSA | CfaAffx.26158.1.S1_at | −1.19907 | 10.3604 | No |
| 12 | DKC1 | Cfa.15181.1.A1_at | −1.00987 | 9.78106 | No |
| 13 | SACS | Cfa.9009.1.A1_s_at | 1.92716 | 8.952 | Yes |
| 14 | SLC25A32 | CfaAffx.1910.1.S1_s_at | 1.14517 | 8.36223 | Yes |
| 15 | Cfa.10817.1.A1_at | 1.64832 | 8.14561 | Yes | |
| 16 | LOC100856757 | CfaAffx.12913.1.S1_at | 1.17254 | 7.92665 | Yes |
| 17 | STK4 | Cfa.11970.1.A1_s_at | 1.45166 | 7.68948 | Yes |
| 18 | PDK4 | Cfa.2282.1.S1_at | 1.44404 | 7.5243 | Yes |
| 19 | LOC100856610 | CfaAffx.7874.1.S1_at | 1.04913 | 7.36905 | Yes |
| 20 | TOMM40 | CfaAffx.7881.1.S1_at | 1.09175 | 7.22431 | Yes |
| 21 | MPP6 | Cfa.19439.1.S1_s_at | −1.06586 | 7.00514 | No |
| 22 | TPMT | Cfa.13501.1.S1_at | −1.26947 | 6.75627 | Yes |
| 23 | Cfa.5147.1.A1_at | −1.00366 | 6.7445 | No | |
| 24 | DDX27 | Cfa.16395.1.S1_s_at | −1.2651 | 6.72183 | Yes |
| 25 | GNL3 | Cfa.728.1.S1_at | −1.06477 | 6.69788 | Yes |
| 26 | ATAD3B | CfaAffx.29389.1.S1_s_at | 1.07357 | 6.67137 | Yes |
| 27 | PTER | CfaAffx.7837.1.S1_at | 1.14624 | 6.43559 | Yes |
| 28 | Cfa.11219.1.A1_at | 1.80816 | 6.28498 | Yes | |
| 29 | ECE2 | CfaAffx.19432.1.S1_at | −1.22996 | 6.12386 | No |
| 30 | SEPT7 | Cfa.19142.1.S1_s_at | −1.66533 | 6.05097 | No |
| 31 | DOHH | Cfa.16291.1.S1_at | 1.57353 | 6.00274 | Yes |
| 32 | ZMYND19 | CfaAffx.29651.1.S1_at | −1.32081 | 5.99707 | Yes |
| 33 | FAM114A2 | Cfa.20692.1.S1_s_at | −1.351 | 5.94761 | Yes |
| 34 | Cfa.14137.1.A1_at | 1.24951 | 5.91518 | Yes | |
| 35 | RBM28 | CfaAffx.3410.1.S1_at | 1.18868 | 5.74236 | No |
| 36 | Cfa.5850.1.A1_at | 1.80063 | 5.65197 | Yes | |
| 37 | Cfa.532.1.S1_at | 1.13559 | 5.65041 | Yes | |
| 38 | SYNCRIP | Cfa.21357.1.S1_s_at | −1.10952 | 5.64882 | No |
| 39 | VASH2 | Cfa.10389.1.S1_at | −1.0515 | 5.64609 | Yes |
| 40 | DNTTIP2 | Cfa.20735.1.S1_s_at | −1.78273 | 5.62785 | No |
| 41 | CS | Cfa.17251.1.S1_s_at | −1.60963 | 5.59711 | Yes |
| 42 | Cfa.2317.1.A1_at | 1.91658 | 5.50254 | Yes | |
| 43 | BLM | Cfa.10357.1.A1_at | 1.84429 | 5.4452 | No |
| 44 | C27H12orf5 | Cfa.18758.1.S1_s_at | −1.36122 | 5.4441 | No |
| 45 | MPP6 | CfaAffx.5143.1.S1_s_at | 1.1381 | 5.29845 | No |
| 46 | DDX18 | CfaAffx.8348.1.S1_s_at | −1.29815 | 5.28791 | No |
| 47 | PAM16 | Cfa.6309.1.A1_x_at | −1.00851 | 5.24061 | No |
| 48 | SDAD1 | Cfa.9228.1.A1_at | −1.05421 | 5.2358 | Yes |
| 49 | ITGB1 | CfaAffx.6707.1.S1_s_at | 1.21637 | 5.17063 | Yes |
| 50 | IMMT | Cfa.3180.2.S1_s_at | −1.96215 | 5.13259 | No |