Table 1.

Demographic, Anthropometric, and Biochemical Characteristics

	eGFR ≥ 60 mL/min (n = 97)	eGFR < 60 mL/min (n = 17)	P Value
Age, y	61.2 ± 9.4	68.0 ± 8.1	.006
Female, %	84.5%	76.5%	.65
Postmenopausal, %	90.2%	76.9%	.30
Height, in.	64.2 ± 3.6	64.5 ± 2.9	.77
Weight, lb	153 ± 39	158 ± 30	.67
BMI, kg/m2	25.8 ± 5.2	26.6 ± 4.7	.56
Race
White, %	90.7	100.0	.22
Black, %	7.2	0.0
Asian, %	2.0	0.0
Ethnicity
Hispanic, %	10.3	5.9	1.0
PHPT characteristics
PHPT duration, y	4.3 ± 5.7	3.3 ± 3.1	.49
Kidney stones, %	18.8	25.0	.72
Osteoporosis, %	40.6	53.3	.54
History of fracture, %	16.7	12.5	1.0
Serum calcium ≥1 mg/dL above limit, %	26.0	12.5	.48
Age <50 y, %	8.3	0.0	.86
Meets surgical guidelines, %	66.0	100.0	.003
Biochemical evaluation
25OHD, ng/mL	34 ± 11	40 ± 12	.04
1,25-dihydroxyvitamin D, pg/mL	71 ± 21	51 ± 20	.0004
Serum calcium, mg/dL	10.6 ± 0.6	10.5 ± 0.5	.34
Serum PTH, pg/mL	92 ± 57	80 ± 31	.43
Phosphate, mg/dL	3.0 ± 0.5	3.0 ± 0.4	.98
Albumin, mg/dL	4.5 ± 0.3	4.5 ± 0.3	.77
Glucose, mg/dL	92 ± 15	96 ± 15	.33
FGF-23, RU/mLa	105 ± 61	110 ± 49	.84
Urine calcium, mg per 24 hb	285 ± 154	182 ± 98	.12
eGFR, mL/min per 1.73 m2	88 ± 14	52 ± 6	N/A

Abbreviation: N/A, not applicable. Results represent mean ± SD or percentage.

^aAvailable for 49 subjects; normal published mean FGF-23 43.6 ± 14.3 RU/mL (16).

^bAvailable for 41 subjects.