Table 1.
Double IIF on Human Pituitary Substrate to Identify the Type of Anterior Pituitary Cells Recognized by the Patient Antibodies
| Type of Cell, n (%)a |
||||||
|---|---|---|---|---|---|---|
| GH | PRL | ACTH | LH | TSH | FSH | |
| Cases (n = 31) | ||||||
| Pituitary adenomas (n = 13) | 0 (0) | 0 (0) | 3 (10) | 3 (10) | 11 (36) | 12 (39) |
| SMOUP (n = 2) | 0 (0) | 0 (0) | 1 (3) | 0 (0) | 1 (3) | 2 (6) |
| Isolated deficiencies (n = 8) | 0 (0) | 1 (3) | 0 (0) | 2 (7) | 7 (23) | 6 (19) |
| Hypophysitis (n = 8) | 1 (3) | 0 (0) | 2 (6) | 3 (10) | 5 (16) | 7 (23) |
| Controls (n = 3) | 0 (0) | 0 (0) | 2 (67) | 0 (0) | 1 (33) | 2 (67) |
| Total positive | 1 | 1 | 8 | 8 | 25 | 29 |
Abbreviations: SMOUP, sellar mass of unknown pathology.
a
Results are shown as number of patient sera recognizing a particular pituitary cell type (n) and percentage of the total patient sera or healthy controls recognizing that cell type.