Activation of cancer pathways in human FTC. Immunohistochemical staining of human normal thyroid (A–D), PTC (E–H), FVPTC (I–L), and FTC (M–P) for pCREB (A, E, I, and M), pERK (B, F, J, and N), pAKT (C, G, K, and O), and phospho-p70S6K (D, H, L, and P). Scale bar (A, applies to all), 500 μm.