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. 2014 Apr 29;8:270. doi: 10.3389/fnhum.2014.00270

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Copyright © 2014 Abhinav, Yeh, El-Dokla, Ferrando, Chang, Lacomis, Friedlander and Fernandez-Miranda.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Baseline scans in patients 4 (A, left lateral view) and 5 (B, posterior view) demonstrating bilateral changes in the motoric and extramotoric pathways, being more pronounced on the right. Bilateral involvement of the cerebellar outflow tracts (Cerebel. outflow) was noted in patient 5. Bilaterally involved tracts in both included corpus callosum (CC); corticospinal tract (Cort-sp.); frontal fibers in the posterior limb of the internal capsule (Int. Cap.) coursing toward the brainstem; cinguli (Cing.) and parts of superior longitudinal (Sup. Long.) and inferior occipito-frontal (Inf. Occ. Fr.) fasciculi.