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. 2014 Apr 29;5:98. doi: 10.3389/fgene.2014.00098

Table 2.

Significant term annotation groups and the gene-list they appeared significant in for the Skin vs. Muscle comparison.

Description Skin.T7.Down Skin.T7.Up Skin.T14.Down Skin.T14.Up Muscle.Down Muscle.Up
ATP biosynthesis X X X
Muscle contraction and development X X X
Mitotic cell cycle checkpoint X X X
pH and lysosome regulation X X X
Neurotransmitter secretion and transport X X
Epithelial tube branching X X
Endocrine regulation of blood pressure X X
Fluid transport X X
Tube development X X
Response to glucose X X
Steriod biosynthesis X
Lung cell differentiation X
Neg regulation of astrocyte diff. X
Fear response X
Dopamine transport X
Collateral sprouting X
Response to osmotic stress X
Positive regulation of epidermal growth factor signaling X
Response to leptin X
Catecholamin biosynthesis X
Microtubule organization X X
Blood vessel endothelial cell differentiation X X
Negative regulation of protein transport X X
Negative regulation of response to granulocyte/myeloid cell diff. X X
Type II hypersensitivity X
Entry into host and movement X
Response to virus X
Mitotic spindle assembly X
N acetylglucosamine metabolism X
Proteoglycan biosynthesis X
Negative regulation of cell junction assembly X
Endocardial cell differentiation X
Sequestering of actin monomers X
Beta amyloid formation X
Response to platelet derived growth factor stimulus X
Lipopolysaccharide biosynthesis X
Aminoglycan metabolism X
Epithelial to mesenchymal transition, endocardial cushion formation X
Pulmonary valve dev. and morphogenesis X
Cellular respiration X X
acetyl CoA biosynthesis X X
Response to muscle activity X X
Protein localization in mitochondrion X
Cation channel activity X
Interferon gamma response X
Calcineurin NFAT signaling cascade X
Histone demethylation X
Negative regulation of Ras signal transduction X
Positive regulation of metalloenzyme activity X
Glucocorticoid receptor signaling pathway X
Atrioventricular valve dev. and morphogenesis X X
Vitamin metabolism X X
Digestion X
Synapse assembly and nervous system development X
Folic acid compound metabolism X
Retinoic acid biosynthesis X
Urea cycle X
Response to prostaglandin X
Keratinocyte migration X
Amino acid transport X
Mesenchymal cell diff in kidney/Renal system dev. X
Axon extension X
Lung lobe dev. and morphogenesis X
Embryonic digestive tract dev. and morphogenesis X
Phosphate ion transport X
Fluid secretion X
Interleukin 13 production X
Glia guided migration X
Central nervous system maturation X
Bile acid transport X
Positive regulation of muscle cell apoptosis X
Purine metabolism X
Regulation of phospholipase C X
Response to VEGF X
Membrane repolarization X
Carbohydrate catabolism X
rRNA processing X
Response to indole 3 methanol X
DNA break repair X