Table 4.

Significant term annotation groups and the gene-list they appeared significant in for the CROHNS vs. UC comparison.

Description	UC.Down	UC.Up	CROHNS.Down	CROHNS.Up
Hydrogen peroxide metabolism		X		X
Nucleotide and nucleoside metabolism		X		X
Amine metabolism		X		X
Extrinsic signal transduction		X		X
Regulation of nitric-oxide synthase		X		X
Fatty-acyl-CoA biosynthesis		X		X
Chemokine and cytokine production		X		X
ER unfolded protein response		X		X
Antigen processing and presentation		X		X
Response to lipopolysaccharide and bacterial		X
Regulation of inflammatory response		X
Regulation of cell cycle and DNA damage response		X
Regulation of ubiquitination and ligase activity		X
nik/nk-kappab cascade		X
Regulation of ras/rac/rho gtpase activity		X
COPII vesicle coating and targeting		X
Negative regulation of peptidase activity		X
Response to type 1 interferon		X
Protein N-linked glycosylation		X
Glandular cell differentiation	X
Membrane biogenesis and assembly	X
Activin receptor signaling	X
Oligodendrocyte differentiation	X		X
Cellular pattern specification	X		X
NAD biosynthesis				X
Hormone metabolism				X
Response to growth hormone				X
Melanin metabolism				X
Protein dephosphorylation				X