TABLE 1 .
Summary of bacterium-mediated epigenetic modifications to viruses
| Bacteria | Virus | Interaction | Viral epigenetic modification(s) | Reference(s) |
|---|---|---|---|---|
| P. gingivalis | KSHV | Direct | Global H3 and H4 acetylation | 31 |
| EBV | Direct | H3 acetylation and HDAC dissociation from BZLF1 promoter | 46 | |
| Periodontitis-associated bacteria | HPV | Indirect | DNA hypomethylation | 56, 57, 62–64 |
|
P. gingivalis, F. nucleatum, C. cochlearium, E. multiforme, A. tetradius, (Butyrate) |
HIV | Direct | Increased H3K4me2, H3ac, and H4ac, decreased H3K9me3, RNAPII binding, HDAC1 dissociation at LTR |
48, 49, 69, 70, 75 |
| H. pylori | EBV | Indirect | DNA hypermethylation | 76, 81–97 |