Table 3.
Morbidity Measures for the Wheeze Clusters at 18-years
| Cluster 1 (n=38) % (count) |
Cluster 2 (n=75) % (count) |
Cluster 3 (n=30) % (count) |
Cluster 4 (n=60) % (count) |
Cluster 5 (n=76) % (count) |
Cluster 6 (n=30) % (count) |
p-value | |
|---|---|---|---|---|---|---|---|
| Wheezing attacks in 12 months |
0.06 | ||||||
| None | 16.2 (6) | 16.4 (12) | 6.9 (2) | 8.5 (5) | 26.7 (20) | 10.0 (3) | |
| 1 to 3 | 56.8 (21) | 57.5 (42) | 55.2 (16) | 52.5 (31) | 48.0 (36) | 50.0 (15) | |
| 4 to 12 | 18.9 (7) | 17.81 (13) | 20.7 (6) | 18.6 (11) | 22.7 (17) | 30.0 (9) | |
| >12 | 8.1 (3) | 8.2 (6) | 17.24 (5) | 20.3 (12) | 2.7 (2) | 10.0 (3) | |
| Sleep disturbance | 10.8 (4) | 13.9 (10) | 21.4 (6) | 22.8 (13) | 8.6 (6) | 24.0 (6) | 0.17 |
| Limited speech | 13.5 (5) | 18.3 (13) | 10.7 (3) | 25.9 (15) | 15.7 (11) | 3.9 (1) | 0.17 |
| Limited Exercise | 68.4 (26) | 75.7 (56) | 86.2 (25) | 69.5 (41) | 67.1 (51) | 73.3 (22) | 0.44 |
| Mean No. of overnight Hospital admissions |
0.14 | 0.13 | 0.14 | 0.02 | 0.04 | 0.03 | 0.30 |
| Mean No. of A&E visits |
0.22 | 0.26 | 0.25 | 0.03 | 0.09 | 0.19 | 0.17 |
Sleep Disturbance; Sleep disturbed by wheeze in the past year.
Speech Limitation; Speech limited by wheezing in the past year.
Exercise Limitation; Exercise limited by wheezing in the past year.
Healthcare utilisation refers to between the ages of 10-18-years;
Overnight Hospital Admissions; Overnight hospital admissions for wheezing.
A&E/Ward visits; Attendance with wheezing at Accident & Emergency or day ward without need for admission.
the p-values are for the tests comparing the distribution patterns of a categorical variable in each cluster or comparing medians (continuous variables) across the 6 clusters. For categorical variables, chi-square tests were implemented and for continuous variables Kruskal-Wallis tests were used due to the violation of the normality assumption in the residuals.