Table 1. Baseline characteristics of study subjects and weight over time.

Baseline characteristics
	NB32		Placebo
	Mean±s.d.	Range	Mean±s.d.	Range
Age (years)	30.9±7.8	20–44	31.4±8.5	19–45
BMI (kg m−2)	33.0±4.6	27.7–40.4	32.0±3.2	27.3–37.6
Weight over time
	NB32	Placebo	Placebo-corrected difference	P-value
Weight
Baseline (kg)	87.9±17.0	90.3±14.2	NA	NA
% Change at week 4	−0.99±0.44	−0.43±0.44	−0.56	0.38

Abbreviations: BMI, body mass index; NA, not applicable; NB32, naltrexone-sustained release (SR) 32 mg and bupropion SR 360 mg.

Baseline values are mean±s.d. Changes are least square mean±s.e.

N=20 for both NB32 and placebo groups.