Table 2. Spatial coordinates of significant activated clusters during food video stimulation in the MNI stereotactic space (P<0.05; t-tests). Average t-score values in isotropic cubic regions of interest (27 voxels; 0.73 cc) centered at the (x, y, z) coordinates.
| Region |
Coordinates |
t-score |
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
mm |
PL |
NB |
PL>NB |
NB>PL |
NB>PL |
||||||||
| BA | x | y | z | BL | Tx | Tx>BL | BL | Tx | Tx>BL | BL | Tx | (Tx>BL) | |
| Superior frontal | 32 | −12 | 39 | 39 | NS | NS | −3.3 | NS | 3.7 | NS | NS | 3.8 | 4.2 |
| Anterior cingulate | 32 | −9 | 30 | 33 | NS | NS | −4.7 | NS | 3.8 | NS | NS | 4.1 | 4.8 |
| Hippocampus | 20 | 36 | −27 | −12 | 4.4 | NS | NS | NS | 4.7 | 4.4 | NS | 3.4 | 4.0 |
| Hippocampus | 20 | 33 | −6 | −27 | NS | NS | −6.0 | NS | NS | NS | NS | NS | 3.4 |
| Superior parietal | 5 | 18 | −45 | 66 | 3.2 | −3.6 | NS | NS | NS | 3.2 | NS | 3.8 | 4.4 |
| Posterior insula | 48 | 42 | −30 | 18 | 3.6 | NS | NS | NS | NS | 3.6 | NS | 3.1 | 4.0 |
Abbreviations: BA, Brodmann area; BL, baseline (food cue>neutral cue); MNI, Montreal Neurological Institute; NB, NB32 group; NB>PL(Tx>BL), group × treatment interaction; NS, not significant; PL, placebo group; Tx, after 4-week treatment (food cue>neutral cue). Tx>BL, treatment interaction.
N=20 for both the NB32 and placebo groups.