FIG 2.

Geographic distribution of the LAM family and its sublineages and major spoligotypes. Numbers in italics show percentages of LAM isolates in the local population of M. tuberculosis (also roughly reflected by the circle size). The prevalence of LAM isolates in St. Petersburg was estimated to be 25% based on an analysis of the IS6110-RFLP database of our laboratory in the light of previously reported LAM-RUS IS6110-RFLP profiles (23). Data on Tula were reported previously (8, 23). Map source, Free World Maps (http://www.freeworldmaps.net/pdf/world/ApianGlobular1.pdf).