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. Author manuscript; available in PMC: 2014 May 6.
Published in final edited form as: Dev Biol. 2007 Jul 10;309(1):137–149. doi: 10.1016/j.ydbio.2007.07.002

Figure 3. Loss of p190-B results in reduced epithelial content and a marked reduction in mammary mesenchyme.

Figure 3

p63 expression in the epithelium of E14.5 mammary buds of (a)p190-B wildtype, (b)p190-B heterozygous & (c)p190-B deficient mice. Androgen receptor (AR) is expressed in the condensed mesenchyme surrounding the epithelial buds in (d) wildtype and (e) heterozygotes, however, the number of cells expressing AR are dramatically reduced in p190-B-deficient embryonic mammary buds (f). Quantitation of these staining patterns (g) show a statistically significant decrease in the number of p63-positive cells within the bud of the p190-B deficient embryos as well as a statistically significant decrease in the number of AR-positive cells within both the p190-B heterozygous and deficient anlagen as compared to the wildtype. Scale bar 100 μm.