Table 5.
Sequences of HIV-1 protease variants.
| Residues | HIV-1 protease | Sequences * |
|---|---|---|
| 1–50 | NL4-3 | PQITLWKRPL VTIKIGGQLK EALLDTGADD TVLEEMNLPG RWKPKMIGGI |
| MDR 769 | PQITLWKRPI VTIKIGGQLK EALLDTGADD TVLEEVNLPG RWKPKLIGGI | |
| MDR 807 | PQITLWKRPI VTIKIGGQLK EALLDTGADD TVLEEMNLPG KWKPKIIVGI | |
| MDR 1385 | PQITLWKRPF VTIKIGGQLK EALLDTGADD TVLEEIDLPG RWKPKIIGGI | |
| MDR 3761 | PQITLWKRPI VAIKVGGQII EALLDTGADD TVLEEMNLPG RWKPKIIGGI | |
| 51–99 | NL4-3 | GGFIKVRQYD QILIEICGHK AIGTVLVGPT PVNIIGRNLL TQIGCTLNF |
| MDR 769 | GGFVKVRQYD QVPIEICGHK VIGTVLVGPT PANVIGRNLM TQIGCTLNF | |
| MDR 807 | GGFTKVRQYD NVQIEICGHK VIGAVLIGPT PANIIGRNLL TQLGCTLNF | |
| MDR 1385 | GGFIKVKQYD QIPIEICGHK VIGTVLVGPT PTNIIGRNMM TQLGCTLNF | |
| MDR 3761 | GGFIKVRQYD QIPVEICGHK IITTVLVGST PVNVIGRNLM TQLGCTLNF |
* The polymorphic changes are underlined. The drug-resistance mutations are in bold.