Fig. 3.

The final orientation of the daughter cell interface is independent of cell shape. (A) The indicated cell is an early proliferative chondrocyte that lacks the oriented disc shape of more mature chondrocyte (circle with arrowhead). The arrows indicate orientation of nearby columns. (B-E) Time-lapse analysis shows that mitosis in this cell occurs perpendicular to the long axis of the cell (C), but the final orientation of the rotation aligns perpendicular to the long axis of the growth plate rather than in a cell-shape-dependent manner (E).