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. 2014 May;141(10):2139–2149. doi: 10.1242/dev.107029

Fig. 6.

Fig. 6.

FLCs are retained and function independently in perinatal life. (A) Immunolocalisation of LCs (HSD3B) and (B) circulating testosterone in adult (pnd60) wild-type and Amh-Cre:DTA testes (t-test, n=3-6). (C) FLCs (HSD3B) in Amh-Cre:iDTR animals 4 d and 13 d following SC ablation at pnd2. Note retention of the FLC population despite SC, GC and PTMC loss. (D) Comparative testicular expression of steroidogenic transcripts 4 d following SC ablation at pnd2, when only FLCs are present (t-tests, n=7-9; *P<0.05, **P<0.01, ****P<0.0001; ns, not significant). Scale bars: 100 µm.