Table VI.
Association Analysis of PIP4K2A SNPs in the FH− Cases Compared to Controls
| SNP | Case freq | Control freq | Chi-sq | P | Perm P | Odds ratio |
|---|---|---|---|---|---|---|
| rs1417374 | 0.343 | 0.282 | 8.54 | 0.004 | 0.024 | 1.22 |
| rs1409395 | 0.367 | 0.317 | 5.43 | 0.020 | 0.158 | 1.16 |
| rs10828317 | 0.351 | 0.322 | 1.97 | 0.161 | 0.807 | 1.09 |
| rs746203 | 0.414 | 0.368 | 4.68 | 0.031 | 0.230 | 1.13 |
| rs8341 | 0.401 | 0.355 | 4.51 | 0.034 | 0.247 | 1.13 |
| rs1417374-rs1409395 | ||||||
| Haplotype | ||||||
| 1-1 | 0.54 | 0.59 | 8.869 | 0.0008 | 0.004 | 0.88 |
| 1–2 | 0.11 | 0.09 | 1.497 | 0.033 | 0.590 | 1.20 |
| 2-1 | 0.14 | 0.13 | 1.413 | 0.366 | 0.985 | 1.10 |
| 2-2 | 0.22 | 0.19 | 3.019 | 0.032 | 0.242 | 1.24 |
Significant (uncorrected) P-values are in bold.