Table 1. Demographic characteristics of subjects enrolled in single- and multiple-dose studies. Values were shown as mean±SD (range).

	0.5 mg/kg (n=8)	Single-dose (part one) 1.0 mg/kg (n=8)	2.0 mg/kg (n=8)	Multiple-dose (part two) 1.0 mg/kg (n=10)
Age (years)	22.8±1.4 (20–24)	22.1±1.6 (20–24)	22.1±1.5 (20–24)	35.5±1.4 (19–48)
Sex	0 female, 8 male	0 female, 8 male	0 female, 8 male	5 female, 5 male
Height (cm)	168.3±5.5 (166–171)	166.9±5.4 (165–172)	167.6±5.9 (165–174)	166.4±2.9 (163–171)
Weight (kg)	61.8±6.6 (57–68)	59.6±5.0 (56–69)	58.2±3.5 (55–70)	61.2±3.9 (58–71)