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. 2012 Jul 16;33(8):991–997. doi: 10.1038/aps.2012.66

Figure 1.

Figure 1

Total protein and MIP-2 in BALF in the control, HVZP, and HVZP+tPA groups. All rats were randomly divided into three groups: the control group (n=7) did not receive ventilation; the HVZP group (n=7) received 2 h of ventilation at a tidal volume of 30 ml/kg, a respiratory rate of 25 breaths/min, and an FiO2 of 0.21; and the HVZP+tPA group (n=7) received an intravenous injection of tPA (1.25 mg/kg) 15 min before the HVZP ventilation. (A) Rats that received HVZP and HVZP+tPA ventilation had significantly higher bronchoalveolar lavage fluid (BALF) total protein contents than that of the control group (cP<0.01 vs control group). Compared to the HVZP group, the HVZP+tPA group had significantly lower BALF protein content (eP<0.05 vs HVZP group). (B) MIP-2 concentrations in BALF were significantly higher in rats of the HVZP and HVZP+tPA groups than in the control group (cP<0.01 vs control group).