Table 2. Lung injury score in the control, the high-volume zero positive end-expiratory pressure (HVZP), and the HVZP+tissue plasminogen activator (tPA) group. Values are expressed as median (range). cP<0.01 vs control group; fP<0.01 vs HVZP group.
Treatment | n | Alveolar congestion | Hemorrhage | Alveolar thickness | Neutrophil infiltration | Lung injury score |
---|---|---|---|---|---|---|
Control | 7 | 0 (0–1) | 1 (0–2) | 0 (0–1) | 1 (1–2) | 2 (1–3) |
HVZP | 7 | 3 (2–4) | 3 (2–4) | 2 (2–4) | 2 (1–2) | 10 (7–14)c |
HVZP+tPA | 7 | 1 (1–2) | 2 (1–2) | 2 (1–2) | 1 (1–2) | 6 (5–7)cf |