Table 1. The mean physiological parameters used in the WB-PBPK absorption models.

Gut compartment	pH	Transit time (h)	Volume (mL)	Length (cm)	Radius (cm)
Stomach	1.3	0.25	50	30	10
Duodenum	6	0.26	48	15	1.6
Jejunum 1	6.2	0.95	175	62	1.5
Jejunum 2	6.4	0.76	140	62	1.34
Ileum 1	6.6	0.59	108	62	1.18
Ileum 2	6.9	0.43	79	62	1.01
Ileum 3	7.4	0.31	56	62	0.85
Caecum	6.4	4.5	53	14	3.5
Ascending colon	6.8	13.5	57	29	2.5