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. 2014 May 1;23(5):382–388. doi: 10.1089/jwh.2012.4200

Table 3.

Proportion of Women Who, After Using Menopausal Hormone Therapy 2005–2006 and Having at Least One Failed Attempt to Discontinue It, Resumed It After Experiencing, Being Bothered by, or Citing a Symptom, by Discontinuation Success

Symptoms upon HT discontinuation Not successful n=337% yes Successfully quit HT n=465% yes
Hot flashes 75 75
 Extremely bothered (vs. none/somewhat) (p≤0.001)a 70 41
 Was this a reason for going back on HT? (p≤0.001) 87 65
Trouble sleepinga 74 57
 Extremely bothered (vs. none/somewhat) (p≤0.001) 63 42
 Was this a reason for going back on HT? (p≤0.001) 75 54
Vaginal dryness/irritation 41 44
 Extremely bothered (vs. none/somewhat) (p≤0.001) 41 24
 Was this a reason for going back on HT? (p≤0.001) 54 24
Moods swings or depressiona 51 34
 Extremely bothered (vs. none/somewhat) (p≤0.001) 48 26
 Was this a reason for going back on HT? (p≤0.001) 81 43
Fatigue, tiredness, low energya 51 38
 Extremely bothered (vs. none/somewhat) (p≤0.01) 50 35
 Was this a reason for going back on HT? (p≤0.001) 69 42
Aches and pains 27 23
 Extremely bothered (vs. none-somewhat) 40 34
 Was this a reason for going back on HT? (p≤0.01) 60 29

Hormone therapy was estrogen with or without progestin.

a

All p values based on chi-square tests.