Table 1.
Baseline characteristics of women with CKD by cardiovascular event status
| Variable | Prior Heart Disease | P Value | |
|---|---|---|---|
| Yes (n=2173) | No (n=4583) | ||
| Age at index (yr), median (IQR) | 75.1 (68.9–79.2) | 73.9 (67.4–78.4) | <0.001 |
| Bisphosphonate prescription, n (%) | 0.24 | ||
| Prevalent | 534 (24.6) | 1157 (25.2) | |
| Incident | 282 (13.0) | 652 (14.2) | |
| None | 1357 (62.4) | 2774 (60.5) | |
| Caucasian, n (%) | 2148 (98.8) | 4525 (98.7) | 0.69 |
| Smoking status, n (%) | <0.001 | ||
| Never | 1137 (57.3) | 2703 (64.7) | |
| Past | 664 (33.5) | 1100 (26.3) | |
| Current | 182 (9.2) | 374 (9.0) | |
| Thyroid disorder, n (%) | 660 (30.4) | 1309 (28.6) | 0.13 |
| Osteoporosis, n (%) | 643 (29.6) | 1452 (31.7) | 0.08 |
| Any rheumatologist visits in the past year, n (%) | 266 (12.2) | 512 (11.2) | 0.20 |
| Aspirin, n (%) | 350 (16.1) | 477 (10.4) | <0.001 |
| Clopidogrel, n (%) | 264 (12.2) | 134 (2.9) | <0.001 |
| β-Blockers, n (%) | 1068 (49.2) | 1644 (35.9) | <0.001 |
| Statins, n (%) | 943 (43.4) | 1635 (35.7) | <0.001 |
| Diabetes, n (%) | 1153 (53.1) | 1767 (38.6) | <0.001 |
| Cardiac dysrhythmia, n (%) | 739 (34.0) | 511 (11.2) | <0.001 |
| Chronic obstructive pulmonary disease, n (%) | 428 (19.7) | 417 (9.1) | <0.001 |
| Peripheral arterial disease, n (%) | 387 (17.8) | 351 (7.7) | <0.001 |
| Atherosclerotic coronary artery disease, n (%) | 943 (43.4) | 798 (17.4) | <0.001 |
| Proteinuria, n (%) | <0.001 | ||
| Not ordered | 925 (42.6) | 2375 (51.8) | |
| Negative | 797 (36.7) | 1513 (33.0) | |
| Positive | 451 (20.8) | 695 (15.2) | |
| Body mass index (kg/m2), median (IQR) | 31.1 (27.3–36.7) | 31.1 (27.1–35.8) | 0.02 |
| Systolic BP (mmHg), median (IQR) | 128.0 (116–140) | 130.0 (120–142) | <0.001 |
| Diastolic BP (mmHg), median (IQR) | 70.0 (60–76) | 70.0 (64–80) | <0.001 |
| Albumin (g/dl), median (IQR) | 4.1 (3.8–4.3) | 4.1 (3.9–4.3) | <0.001 |
| LDL (mg/dl), median (IQR) | 89.0 (70–113) | 100.0 (79–126) | <0.001 |
| HDL (mg/dl), median (IQR) | 49.0 (41–58) | 52.0 (44–62) | <0.001 |
| eGFR (ml/min per 1.73 m2), median (IQR) | 53.7 (46.2–57.2) | 54.2 (47.8–57.6) | <0.001 |
| Number of visits to PCP 12 mo before index date, median (IQR) | 5.0 (3–7) | 4.0 (2–6) | <0.001 |
IQR, interquartile range; PCP, primary care physician.