Table 2.
Independent association of BMI with individual steps in deceased donor transplant process
| Step in Deceased Donor Transplant Process | Men | Women |
|---|---|---|
| Hazard Ratio (95% Confidence Interval) | Hazard Ratio (95% Confidence Interval) | |
| Activation to the waiting list | ||
| Patients (n) | 395,812 | 306,644 |
| BMI (kg/m2) | ||
| <18.5 | 0.92 (0.88 to 0.96) | 0.90 (0.87 to 0.93) |
| 18.5–24.9 | 1.00 | 1.00 |
| 25.0–29.9 | 1.26 (1.23 to 1.29) | 1.07 (1.04 to 1.10) |
| 30.0–34.9 | 1.36 (1.32 to 1.39) | 1.10 (1.06 to 1.13) |
| 35.0–39.9 | 1.12 (1.08 to 1.17) | 0.84 (0.81 to 0.88) |
| ≥40.0 | 0.74 (0.71 to 0.78) | 0.50 (0.48 to 0.53) |
| Transplantation from a deceased donor after wait-listing | ||
| Patients (n) | 84,939 | 57,662 |
| BMI (kg/m2) | ||
| <18.5 | 1.04 (0.99 to 1.10) | 0.98 (0.92 to 1.04) |
| 18.5–24.9 | 1.00 | 1.00 |
| 25.0–29.9 | 1.00 (0.97 to 1.03) | 0.92 (0.88 to 0.96) |
| 30.0–34.9 | 0.99 (0.95 to 1.03) | 0.87 (0.83 to 0.92) |
| 35.0–39.9 | 0.88 (0.83 to 0.93) | 0.77 (0.72 to 0.82) |
| ≥40.0 | 0.72 (0.66 to 0.78) | 0.65 (0.59 to 0.71) |
Separate multivariate Cox regression models were performed in men and women for the outcome of activation to the waiting list, and transplantation from a deceased donor after wait-listing. All models included adjustment for the following factors: age, race, cause of ESRD, history of comorbid conditions (ischemic heart disease, cerebrovascular accident, congestive heart failure, peripheral vascular disease, cancer), functional status, year of first ESRD treatment, type of medical insurance, and RUCA codes. The Cox models for the outcome of deceased donor transplantation after wait-listing also included adjustment for ABO blood group and panel reactive antibodies.