Table 2.

Univariate and multivariate Cox regression analyses with ESRD^a as the end point in 283 patients with IgA nephropathy

Analysis	β	P Value	Hazard Ratio (95% Confidence Interval)
Univariate
Age (yr)	0.02	0.001	1.02 (1.01 to 1.04)
Positive C4d staining	1.53	<0.001	4.65 (2.63 to 8.22)
Hypertension	1.84	<0.001	6.30 (2.98 to 13.31)
Proteinuria (g/d)	0.25	<0.001	1.28 (1.16 to 1.43)
eGFR (ml/min per 1.73 m2)	−0.04	<0.001	0.95 (0.94 to 0.96)
Oxford classification
S1	1.10	<0.001	3.02 (1.76 to 5.16)
T0			1 (reference)
T1	1.93	<0.001	6.89 (2.31 to 20.5)
T2	3.27	<0.001	26.23 (9.23 to 75.43)
Multivariate
Positive C4d staining	0.89	0.01	2.45 (1.30 to 4.64)
Proteinuria (g/d)	0.15	0.01	1.16 (1.03 to 1.31)
eGFR (ml/min per 1.73 m2)	−0.04	<0.001	0.96 (0.94 to 0.97)
Oxford classification
T0			1 (reference)
T2	1.48	0.01	4.42 (1.40 to 13.88)

^aESRD: chronic dialysis or renal transplantation.