Table 3.
Multivariable logistic regression analysis of factors associated with CKD (eGFR<60 ml/min per 1.73 m2) in those patients with PH (n=1088)
| Effect | Odds Ratio (95% Confidence Interval)a |
|---|---|
| Age (for each 10 yr higher) | 1.69 (1.51 to 1.90) |
| Women | 1.00 (0.74 to 1.36) |
| African-American race | 0.70 (0.48 to 1.04) |
| Diabetes | 1.18 (0.85 to 1.64) |
| Hypertension | 1.35 (1.01 to 1.82) |
| Systolic failure (EF<40%) | 1.78 (1.02 to 3.11) |
| Hemoglobin (for each 1 g/dl higher) | 0.90 (0.84 to 0.96) |
| Albumin (for each 1 mg/dl higher) | 0.86 (0.66 to 1.11) |
| Mean right atrial pressure (for each 1 mmHg higher) | 1.04 (1.02 to 1.07) |
| Pulmonary arterial diastolic pressure (for each 1 mmHg higher) | 1.00 (0.98 to 1.01) |
| PH class | |
| I (PAH) | Reference |
| II (PVH) | 0.63 (0.41 to 0.95) |
| III (PH lung disease) | 0.71 (0.44 to 1.15) |
| IV (PH CTED) | 0.45 (0.21 to 0.96) |
| V (miscellaneous) | 0.75 (0.43 to 1.29) |
a
Adjusted for age, sex, race, diabetes, hypertension, EF<40%, hemoglobin, albumin, mean right atrial pressure, pulmonary arterial diastolic pressure, pulmonary capillary wedge pressure, medications (diuretics and angiotensin-converting enzyme inhibitors/angiotensin receptor blockers), pulmonary hypertension classification, and dummy indicators of missing data.