Fig. 6.

(A) The profile of f(C) as a function of C given different values of λ_c. Each line represents a different value of λ_c. The parameter λ_c increases from the top curve to the bottom curve, and the ratio of the λ_c’s of neighboring two curves is 1.25 fold. The steady state cancer size is where a curve decreases from positive to negative. The two thick blue curves have λ_c = 8.77e−7 and 1.07e−6 and correspond to λ₁ and λ₂ in (B). (B) Nonzero solutions of f (C) = 0 as a function of λ_c. Solid lines: stable steady states of the model; dashed line and open circles: unstable steady states. The dotted lines indicate the values of λ₁ and λ₂ where the saddle node bifurcations occur. (For interpretation of the references to color in this figure caption, the reader is referred to the web version of this article.)