Figure 3.

Enhanced anti-proliferative activity (A) and induction of apoptosis (B) of gemcitabine when administered in combination with icariin and representative cytometric apoptosis graphs (C). Cells were treated with both icariin (40 μg/mL) and gemcitabine (0.5 μmol/L) for 24 h. Cell viability was analyzed by the MTT assay, and apoptosis was measured by flow cytometry. Mean±SD. n=3. ^bP<0.05, ^cP<0.01 vs the vehicle.