Table 3. Periodontal semi-quantitative analysis for inflammatory cell influx, edema, fibrosis and necrosis in gingivomucosal tissue of the patients.
| Parameter | SRP+placebo |
SRP+SDD |
||||
|---|---|---|---|---|---|---|
| Baseline mean±SD | 3 month mean±SD | P | Baseline mean±SD | 3 month mean±SD | P | |
| PMN | 3±0.10 | 2.09±0.05 | 4.31E-13 | 2.90±0.08 | 1.81±0.04 | 2.39E-29 |
| Monocytes | 2.09±0.07 | 1.97±0.04 | 0.0482 | 2.09±0.09 | 1.81±0.07 | 0.0045 |
| Eosinophils | 0.81±0.04 | 0.63±0.05 | 0.0432 | 0.81±0.04 | 0.63±0.05 | 0.0553 |
| Edema | 3.84±0.05 | 3±0.08 | 0.0269 | 3.72±0.08 | 3.72±0.04 | 0.0052 |
| Fibrosis | 1.98±0.07 | 1±0.08 | 8.3E-16 | 2±0.06 | 1.95±0.08 | 3.07E-18 |
| Necrosis | 3.98±0.07 | 3.88±0.08 | 0.0324 | 3.89±0.06 | 3.82±0.04 | 0.0038 |
PMN=polymorphonuclear leukocytes; SRP=scaling and root planning; SDD=subantimicrobial-dose doxycycline; P=statistical significance baseline compared with 3 months.