Figure 2.

Effects of [6]-shogaol on tyrosinase activities. (A) Effect of [6]-shogaol on intracellular tyrosinase activity was studied after B16 cells were treated with [6]-shogaol at the indicated concentrations for 2 d. (B) Direct effect of [6]-shogaol on tyrosinase activity was measured using mushroom tyrosinase in a cell-free system. Kojic acid was used as a positive control. Con, DMSO-only vehicle control. Data are reported as the mean±SEM of three independent experiments carried out in triplicate. ^bP<0.05, ^cP<0.01 vs control.