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. 2012 Nov 12;34(2):255–261. doi: 10.1038/aps.2012.144

Table 1. Distribution of gene polymorphisms and association results for type 2 diabetes.

  Type 2 diabetes patients group Healthy control group ΔP OR (95% CI) (Univariate analysis) #P OR (95% CI) (Multivariate analysis) P
Genotype frequency   n % n %          
PPAR-γ2 rs1801282
  CC 180 91.37 180 84.91   1   1  
  CG 17 8.63 32 15.09 0.044b 0.531 (0.285–0.991) 0.047b 0.515 (0.268–0.990) 0.047b
PTPRD rs17584499
  CC 145 73.60 179 84.43   1   1  
  CT 49 24.87 31 14.62 0.026b 1.945 (1.194–3.169) 0.008c 1.984 (1.135–3.469) 0.016b
  TT 3 1.52 2 0.94          
Allele frequency   n % n %          
PPAR-γ2 rs1801282
  C 377 95.69 392 92.45          
  G 17 4.31 32 7.55 0.052 0.552 (0.302–1.012) 0.055 0.544 (0.290–1.020) 0.058
PTPRD rs17584499
  C 339 86.04 389 91.75          
  T 55 13.96 35 8.25 0.009c 1.793 (1.145–2.806) 0.011b 1.904 (1.137–3.189) 0.014b

ΔP values: for comparison between type 2 diabetes patients and healthy control by χ2 test;

#P values and their ORs: for comparison between genotypes by logistic regression analysis in dominant model;

P values and their ORs: for multivariate analyses after adjusted for age, gender and BMI.

bP<0.05,

cP<0.01.