Table 3. The baseline characteristics of all type 2 diabetes patients with various genotypes for the PPAR-γ2 rs1801282 and PTPRD rs17584499 polymorphisms before the administration of pioglitazone (n=67).
Parameters | PPAR-γ2 rs1801282 |
|
PTPRD rs17584499 |
|
||
---|---|---|---|---|---|---|
CC | CG | P | CC | CT+TT | P | |
No (male/female) | 60 (35/25) | 7 (4/3) | 0.952Δ | 45 (24/21) | 22 (15/7) | 0.247Δ |
Age (year) | 56.77±8.34 | 55.43±10.41 | 0.704† | 55.62±7.98 | 58.68±9.33 | 0.100† |
Duration (month) | 41.67±35.22 | 67.71±63.57 | 0.367† | 42.16±39.34 | 48.96±39.58 | 0.389† |
BMI | 25.29±2.79 | 23.91±2.39 | 0.213# | 25.18±2.59 | 25.07±3.17 | 0.713† |
FPG (mmol/L) | 8.25±1.18 | 9.16±1.12 | 0.056# | 8.36±1.28 | 8.30±1.05 | 0.989† |
PPG (mmol/L) | 13.17±3.30 | 12.94±2.89 | 1.000† | 13.48±3.24 | 12.46±3.20 | 0.225# |
HbA1c (%) | 7.49±1.26 | 8.03±1.78 | 0.492† | 7.65±1.29 | 7.34±1.36 | 0.216† |
TC (mmol/L) | 4.99±0.92 | 5.23±1.08 | 0.608† | 5.09±0.98 | 4.86±0.82 | 0.530† |
TG (mmol/L) | 1.96±1.14 | 2.40±1.17 | 0.223† | 2.06±1.22 | 1.88±0.97 | 0.694† |
HDL-c (mmol/L) | 1.10±0.32 | 1.24±0.29 | 0.223† | 1.13±0.36 | 1.09±0.19 | 0.298† |
LDL-c (mmol/L) | 3.02±0.82 | 3.18±0.89 | 0.697† | 3.06±0.90 | 2.98±0.64 | 0.841† |
BMI, body mass index; FPG, fasting plasma glucose; PPG, postprandial plasma glucose; HbA1c, glycated hemoglobin; TC, total cholesterol; TG, triglyceride; HDL-c, high-density lipoprotein cholesterol; LDL-c, low-density lipoprotein cholesterol.
ΔP values are determined by Pearson χ2 test.
#P values are assessed by two-sample t-test.
†P values are determined by Mann-Whitney test.