Table 2. Compartment model parameters of Re.

Group/Parameter	AUC(0–t) (ng/mL·min)	AUC(0–∞) (ng/mL·min)	t1/2z (min)	tmax (min)	Cmax (ng/mL)
50 mg/kg	757.78	857.72	129.40	60	3.72
25 mg/kg	379.69	484.39	151.88	60	2.19
12.5 mg/kg	166.28	177.79	143.94	60	0.56

^a PK parameters of Re were determined by DAS, n=3 in each dose level.