Table 1.
Case series examining acute and chronic food protein-induced enterocolitis syndrome
| References | Data on all food triggers | Study design | Definition | Country | No. | Duration (years) | Center | Male (%) | Eczema (%) | FHx atopy (%) | IgE FA (%)a |
| Ruffner et al. [30▪] | Yes | Retrospective | Their own | USA | 462 | 5 | One hospital | 60 | 34 | – | – |
| Frith et al. [25] | Yes | Prospective | Their own | Australia | 90 | 1 | Australia wide | 48 | 46 | 53 | 14 |
| Garcia and Jimenez Diaz [26] | Yes | Retrospective | Sicherer et al. [7] (PC) | Spain | 16 | 12 | Unknown | 63 | – | – | – |
| Jarvinen-Seppo et al. [27] | Yes | Retrospective | Sicherer et al. [7] | USA | 76 | 8 | Single allergy clinic | – | – | – | – |
| Sopo et al. [31▪] | Yes | Retrospective | Their own/Powell [34] | Italy | 66 | 7 | Three allergy clinic | 61 | 9 | 20 | 2 |
| Mehr et al. [29] | Yes | Retrospective | Sicherer et al. [7] | Australia | 35 | 16 | Single allergy clinic | 57 | 51 | – | 11 |
| Fogg et al. [24] | Yes | Prospective | Sicherer et al. [7] | USA | 19 | 1.5 | Single allergy clinic | 53 | 11 | – | – |
| Nowak-Wegrzyn et al. [9]b | Yes | Retrospective | Sicherer et al. [7] | USA | 44 | 5 | Two allergy clinic | 59 | 34 | 77 | – |
| Sicherer et al. [7] | Yes | Retrospective | Their own | USA | 20 | 6 | Single allergy clinic | 44 | 31c | 56c | 15 |
| Katz et al. [28▪▪] | CM only | Prospective | Sicherer et al. [7] | Israel | 44 | 2 | One hospital | 52 | 7 (PC) | – | – |
| Nomura et al. [10]b | CM only | Retrospective | Powell [34] | Japan | 30 | 3 | Japanese database | 50 | – | – | – |
| Hwang et al. [33] | CM/soy only | Prospective | Powell [34] | Korea | 23 | 4 | One hospital | 70 | 0 | – | – |
| Fukuie et al. [32]b | CM/soy/wheat/rice | Not stated | Powell [34] | Japan | 10 | 4 | One hospital | – | 10 | – | – |
| Chung et al. [19] | Not stated | Prospective | Sicherer et al. [7] | Korea | 28 | – | One hospital | – | – | – | – |
| Levy and Danon [22] | Solid food only | Retrospective | Their own | Israel | 6 | 6 | One hospital | 67 | – | – | – |
| Burks et al. [23] | CM/soy | Prospective | Their own | USA | 22 | 1.5 | One hospital | – | – | – | – |
| McDonald et al. [5]b | CM/soy | Prospective | Powell [34] | USA | 10 | – | One hospital | – | – | – | – |
| Powell [3]b | CM/soy | Retrospective | Their own | USA | 9 | – | One hospital | – | – | – | – |
| Gryboski [1]b | CM | Retrospective | None set | USA | 21 | 16 | One hospital | 90 | 14 | 62 | – |
CM, cow milk; FHx, family history; –, not available; PC, personal communication with corresponding author.
aIgE FA = IgE-mediated food allergy (that is positive ssIgE- and IgE-mediated clinical reaction to a separate food protein not causing FPIES).
bIn these series, chronic FPIES or a combination of cases of acute/chronic FPIES was reported.
cData only available for infants with typical FPIES (n = 16).