Table 1. Previously identified ATM-interacting proteins and SNF2H-related chromatin remodelling factors identified in the screen.
Gene Name | Protein ID | − IR | + IR | Uniprot | Peptide | Mol Weight (kDa) | Sequence Length | PEP | Reference |
ATM | IPI00601074 | 18.0345 | 17.871 | 130 | 349.74 | 3,069 | 0 | [44] | |
USP10 | IPI00819631 | 1.327425 | 1.281195 | Q5ZJN4 | 25 | 87.558 | 795 | 1.48E-127 | [45] |
FANCI | IPI00586876 | B0I564 | 1 | 149.29 | 1,338 | 0.018182 | [46] | ||
MCM3 | IPI00604115 | 1.146465 | 1.471155 | Q5ZMN2 | 27 | 91.25 | 812 | 7.62E-123 | [47] |
MCM2 | IPI00577675 | 1.12 | Q5ZLZ1 | 22 | 100.35 | 888 | 1.11E-130 | [48] | |
PPP2A | IPI00589014 | 1.01 | P48463 | 3 | 35.563 | 309 | 8.39E-16 | [49] | |
CHD4 | IPI00598956 | 1.2 | 1.65 | 11 | 215.81 | 1,895 | 7.86E-38 | [50] | |
RFC1 | IPI00683437 | Q5ZKU2 | 1 | 129.19 | 1,153 | 0.001435 | [20] | ||
PCNA | IPI00821596 | 1.130685 | Q9DEA3 | 14 | 29.016 | 263 | 2.69E-109 | [51] | |
RSF1 | IPI00572615 | 1.44654 | 4 | 163.86 | 1,441 | 6.55E-11 | N/D | ||
SNF2H | IPI00577188 | 1.39305 | 21 | 136.85 | 1,198 | 2.36E-134 | N/D | ||
BAZ1A | IPI00585200 | 1.35342 | 2 | 180.23 | 1,571 | 1.85E-05 | N/D | ||
BAZ1B | IPI00820657 | 1 | 164.02 | 1,483 | 5.55E-22 | N/D |
Gene name, protein ID, the relative enrichment ratios compared to an untagged cell line of the un-irradiated and irradiated samples, the Uniprot identifier (if known), the number of peptides identified, the molecular weight of the identified protein, the number of its amino acids, and PEP score are indicated. Proteins previously identified as ATM-interacting proteins are indicated by the relevant reference.