Figure 1. Gene Ontology analysis of IQGAP1-GFP pull-downs. Proteins enriched in the IQGAP1 pull-downs²³ were mapped onto the GO category Biological Process (GOTERM_BP_FAT). Over-represented GO term (P < 0.05) were displayed as network-based enrichment maps (see Methods for details). Each node represents a GO term and each edge connects GO terms that contain at least one common protein. Node area is proportional to the number of proteins that belong to a particular GO term, and node color indicates the p value attributed to the enrichment of a particular GO term. Edge width is proportional to the similarity that exists between two GO terms. Nodes of this network were automatically organized using an algorithm that clusters nodes as a function of their connectivity and were then manually annotated.