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Rat MMA, 100 mmHg, pre-contracted with PGF 2α
| Compound | E max (%) | pEC 50 (M) | p - value |
|---|---|---|---|
| ACh (n = 3) |
33 ± 22 |
N.A. |
0.68 |
| SNP (n = 3) |
70 ± 18 |
8.3 ± 0.7 |
0.066 |
| Sildenafil (n = 3) |
52 ± 20 |
~7 |
0.23 |
| PGE2 (n = 3) |
23 ± 12 |
N.A. |
0.82 |
| PACAP-38 (n = 4) |
22 ± 14 |
N.A. |
0.93 |
| NaCl (n = 3) | 23 ± 4 | N.A. |
p-value for comparing agonist versus the NaCl effect. N.A. = Not Applicable. Values are ± SEM, n given in parenthesis.
