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Rat MMA, 50 mmHg, pre-contracted with 30 mM K +
| Compound | E max (%) | pEC 50 (M) | p - value |
|---|---|---|---|
| ACh (n = 5) |
-26 ± 13 |
N.A. |
0.85 |
| SNP (n = 5) |
67 ± 22; |
6.1 ± 1.3 |
0.015 |
| Sildenafil (n = 5) |
40 ± 17 |
5.7 ± 3.8 |
0.0069 |
| PGE2 (n = 5) |
-31 ± 5 |
N.A. |
0.311 |
| PACAP-38 (n = 5) |
27 ± 8 |
N.A. |
0.94 |
| CGRP (n = 5) |
-1 ± 6 |
~ 8 |
0.0015 |
| NaCl (n = 5) | -24 ± 5 | N.A. |
p-value for comparing agonist versus the NaCl effect. N.A. = Not Applicable. Values are ± SEM, n given in parenthesis.
